Soluble Fas modulates interferon responsiveness
نویسندگان
چکیده
منابع مشابه
Physical training modulates proinflammatory cytokines and the soluble Fas/soluble Fas ligand system in patients with chronic heart failure.
OBJECTIVES We sought to investigate the effects of physical training on circulating proinflammatory cytokines and the soluble apoptosis mediators Fas (sFas) and Fas ligand (sFasL) in patients with chronic heart failure (CHF). BACKGROUND Recent investigations have shown an overexpression of circulating proinflammatory cytokines and soluble apoptosis mediators in patients with CHF, which may be...
متن کاملSoluble Fas and cancer.
Recent studies have revealed an anticipated link between a soluble receptor antagonist for the proapoptotic protein Fas and cancer. In this issue, Ugurel et al. (1) demonstrate that sFas levels correlate with poor prognosis and decreased overall survival in patients with melanoma. On the basis of available evidence, it appears that nonhematopoietic tumor development and progression may represen...
متن کاملSoluble Fas ligand and soluble Fas in ocular fluid of patients with uveitis.
AIMS To investigate the presence of soluble Fas ligand (sFasL) and soluble Fas (sFas) in ocular fluid of patients with uveitis. METHODS Samples of aqueous humour (AH, n=17), vitreous fluid (n=9), and serum (n=60) were collected from patients with uveitis which included Behçet's disease, Vogt-Koyanagi-Harada disease, sarcoidosis, human T lymphotropic virus type 1 (HTLV-I) uveitis, sympathetic ...
متن کاملHighly sensitive ELISA for soluble Fas in serum: increased soluble Fas in the elderly.
We have developed and characterized a highly sensitive ELISA for soluble Fas (sFas) in the serum. The linearity of calibrator range was 0.06-2.00 micrograms/L and the detection limit was 0.01 microgram/L. The average within- and between-run CVs were 3.9% and 3.8%, respectively. The recovery of added sFas to serum was 93-118%. The effects of possible interferences (tryglyceride, hemoglobin, bili...
متن کاملAqueous Humor Levels of Soluble Fas and Fas-ligand in Patients with Primary Open Angle and Pseudoex-foliation Glaucoma
Background: Glaucoma is one of the most common causes of blindness and is usually associated with elevated intraocular pressure. In patients with primary open angle glau-coma the number of trabecular meshwork cells is decreased. Death of the trabecular meshwork cells may be a result of apoptosis. Objective: To investigate the aqueous humor levels of soluble Fas (sFas) and Fas-Ligand (sFasL) in ...
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ژورنال
عنوان ژورنال: Journal of Gastroenterology and Hepatology
سال: 2001
ISSN: 0815-9319,1440-1746
DOI: 10.1046/j.1440-1746.2001.02571.x